Acetyl l carnitine deficiency in patients with major depressive disorder PNAS Could a mitochondrial metabolite known as acetyl L carnitine (LAC) yield a new biomarker for depression and potential new therapies? Dr. Carla Nasca, an @nyugrossman assistant professor of psychiatry and of neuroscience and physiology, Supplements for Depression: A Psychiatrist's Perspective SURUCHI CHANDRA M.D. Study links depression to low blood levels of acetyl L carnitine Acetyl L Carnitine Olympian Labs